Benzoic Acid

Benzoic Acid

SCHEMBL57704

C=CC(=O)O.CC(C)(CO)CO.O=C(O)c1ccccc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D

The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
DAO P14920 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
AKT1 P31749 1/20 0.46
SRD5A2 P31213 2/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
ALDH1A1 P00352 3/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
RXRG P48443 1/20 0.37
TP53 P04637 1/20 0.37
POLB P06746 2/20 0.37
THRA P10827 1/20 0.37
THRB P10828 1/20 0.37
MTNR1A P48039 1/20 0.37
MTNR1B P49286 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL204568 0.89 TSHR (0.61) TSHRDAONAPRTSRD5A2CES2
Benzoic Acid SCHEMBL226249 0.89 TSHR (0.61) TSHRDAONAPRTSRD5A2CES2
Benzoic Acid SCHEMBL28058561 0.86 TSHR (0.41) TSHRDAONAPRTAKT1SRD5A2
Benzene SCHEMBL28282177 0.85 LMNA (0.48) TSHRAKT1ALDH1A1CYP3A4CYP2C9
Benzoic Acid SCHEMBL1288216 0.84 TSHR (0.50) TSHRDAONAPRTAKT1SRD5A2
Benzoic Acid SCHEMBL11514559 0.84 TSHR (0.54) TSHRDAONAPRTSRD5A2CES2
Benzoic Acid SCHEMBL5308914 0.83 TSHR (0.58) TSHRDAONAPRTAKT1SRD5A2
Benzoic Acid SCHEMBL57610 0.83 TSHR (0.45) TSHRDAONAPRTAKT1SRD5A2
Benzoic Acid SCHEMBL4622841 0.83 TSHR (0.45) TSHRDAONAPRTAKT1SRD5A2
Benzoic Acid SCHEMBL30978335 0.83 TSHR (0.70) TSHRDAONAPRTAKT1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3642264-A1 CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF Momentive Performance Materials Inc. (US) 2020-04-29 EP claimed
CN-110770282-A Curable silicone composition, and application and use thereof 莫门蒂夫性能材料股份有限公司 2020-02-07 CN claimed
US-10429029-B2 Organic light emitting display device and method for fabricating the same LG DISPLAY CO., LTD. (KR) 2019-10-01 US claimed
US-10385210-B2 Curable silicone composition and applications and uses thereof MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-08-20 US claimed
WO-2018236679-A1 CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-12-27 WO claimed
US-20180362764-A1 CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. 2018-12-20 US claimed
EP-2757133-B1 UV-CURABLE INK FOR DIRECT PLATE MAKING BY INK-JET PRINTING WITH PREPARATION METHOD AND APPLICATION THEREFOR INST CHEMISTRY CAS (CN) 2016-12-28 EP claimed
US-20140238256-A1 ENVIRONMENT FRIENDLY WATERLESS OFFSET PLATE INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2014-08-28 US claimed
EP-2757133-A1 UV-CURABLE INK FOR DIRECT PLATE MAKING BY INK-JET PRINTING WITH PREPARATION METHOD AND APPLICATION THEREFOR Institute Of Chemistry, Chinese Academy Of Sciences (CN) 2014-07-23 EP claimed
US-8530009-B2 Liquid crystal display device including side supporting means and method of fabricating the same LG DISPLAY CO., LTD. (KR) 2013-09-10 US claimed
EP-1088866-B1 Inks containing glycol ethers and specific polymers for dry time and bleed improvements in ink-jet printing inks HEWLETT PACKARD CO (US) 2004-04-28 EP claimed
EP-0997506-B1 Ink to ink bleed and halo control using specific polymers in ink-jet printing inks HEWLETT PACKARD CO (US) 2004-03-24 EP claimed
US-6500880-B1 PH SENSITIVE ACRYLIC POLYMER OF FIRST INK WILL PRECIPITATE OR FLOCCULATE ONTO PRINT MEDIUM UPON CONTACT WITH SECOND INK WHICH CONTAINS INCOMPATIBLE INORGANIC OR ORGANIC SALTS OR HAS AN APPROPRIATE PH HEWLETT-PACKARD COMAPNY 2002-12-31 US claimed
EP-1201719-A1 Black to color bleed control using specific polymers in ink-jet printing inks containing pigmented inks requiring dispersants Hewlett-Packard Company (US) 2002-05-02 EP claimed
US-6300391-B2 FAST DRYING; CONTROLLED BLEEDING AND HALO HEWLETT-PACKARD COMPANY 2001-10-09 US claimed
US-20010018472-A1 INKS CONTAINING GLYCOL ETHERS AND SPECIFIC POLYMERS FOR DRY TIME AND BLEED IMPROVEMENTS IN INK-JET PRINTING INKS HEWLETT-PACKARD COMPANY 2001-08-30 US claimed
US-6281267-B2 CONTAINING PH-SENSITIVE POLYMER HEWLETT-PACKARD COMPANY 2001-08-28 US claimed
US-20010008908-A1 INK TO INK BLEED AND HALO CONTROL USING SPECIFIC POLYMERS IN INK-JET PRINTING INKS HEWLETT-PACKARD COMPANY 2001-07-19 US claimed
EP-1088866-A1 Inks containing glycol ethers and specific polymers for dry time and bleed improvements in ink-jet printing inks Hewlett-Packard Company (US) 2001-04-04 EP claimed
EP-0997506-A1 Ink to ink bleed and halo control using specific polymers in ink-jet printing inks Hewlett-Packard Company (US) 2000-05-03 EP claimed