Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 4/20 | 0.52 |
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL226249 | 1.00 | TSHR (0.61) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL11514559 | 0.94 | TSHR (0.54) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL6388159 | 0.91 | TSHR (0.57) | TSHRDAONAPRTCES1CES2 | |
| Benzoyl Formic Acid SCHEMBL16046499 | 0.91 | CES2 (0.53) | TSHRDAONAPRTCES1CES2 | |
| Adipic Acid SCHEMBL9064834 | 0.89 | HDAC3 (0.53) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL57704 | 0.89 | TSHR (0.48) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28340983 | 0.89 | TSHR (0.48) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL11126820 | 0.89 | TSHR (0.64) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL27397300 | 0.89 | TSHR (0.64) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL6690767 | 0.88 | RXRA (0.47) | TSHRDAONAPRTCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1576 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4596588-A1 | SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF | China Petroleum & Chemical Corporation (CN) | 2025-08-06 | — | — | EP | claimed |
| US-20250129006-A1 | PRODUCTION OF BENZOIC ACID FROM A BIOMASS | SYENSQO SA (BE) | 2025-04-24 | — | — | US | claimed |
| CN-119592378-A | Efficient acidic cleaning agent and preparation method and application thereof | 深圳市化诚科技有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-119350814-A | Red phosphorus flame-retardant PET engineering plastic and preparation method thereof | 宁波瑞隆新材料科技有限公司 | 2025-01-24 | — | — | CN | claimed |
| CN-119286596-A | Efficient environment-friendly acidic degreasing agent and preparation method thereof | 惠州金晟新电子科技有限公司 | 2025-01-10 | — | — | CN | claimed |
| EP-4380917-A1 | PRODUCTION OF BENZOIC ACID FROM A BIOMASS | SYENSQO SA (BE) | 2024-06-12 | — | — | EP | claimed |
| CN-113402386-B | Synthesis method of neopentyl glycol dibenzoate | 武汉亿科德精细化工有限公司 | 2024-05-03 | — | — | CN | claimed |
| WO-2024088298-A1 | SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国石油化工股份有限公司 | 2024-05-02 | — | — | WO | claimed |
| CN-115093682-B | Glass fiber reinforced PET composite material and preparation method thereof | 宁波华腾首研新材料有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-117836264-A | Benzoic acid production from biomass | 西恩斯科公司 | 2024-04-05 | — | — | CN | claimed |
| US-4357268-A | NEUTRALIZED DIMER OR TRIMER ACID | ALLIED CORPORATION (US) | 1982-11-02 | — | — | US | claimed |
| US-4349503-A | CRYSTALLIZATION; SODIUM NITRITE AS A NUCLEATING AGENT | ALLIED CORPORATION (US) | 1982-09-14 | — | — | US | claimed |
| US-4336343-A | CONTAINING SODIUM CITRATE | MORRIS TOWNSHIP, MORRIS COUNTY (US) | 1982-06-22 | — | — | US | claimed |
| US-4304808-A | HEAT SENSITIVE COMPRISING METAL, ACRYLIC HOT MELT ADHESIVE, PLASTICIZER AND SOLVENT; DECALCOMANIA | JOHNSON, MATTHEY & CO., LIMITED (GB) | 1981-12-08 | — | — | US | claimed |
| US-4284540-A | BLENDED WITH COPOLYMERS OF ALPHA OLEFINS AND UNSATURATED GLYCIDYL ESTERS, AND WITH BARIUM SALTS OF FATTY ACIDS | TORAY INDUSTRIES, INC. (JP) | 1981-08-18 | — | — | US | claimed |
| US-4259225-A | STORAGE STABILITY | DAINIPPON INK & CHEMICALS, INC. (JP) | 1981-03-31 | — | — | US | claimed |
| EP-0017942-A1 | Polyethylene terephthalate molding compositions | TORAY INDUSTRIES, INC. (JP) | 1980-10-29 | — | — | EP | claimed |
| US-4068033-A | Heat-releasable decalcomanias and adhesive composition therefor | COMMERCIAL DECAL, INC. (US) | 1978-01-10 | — | — | US | claimed |
| US-4018728-A | PIGMENTARY MATERIALS, HOT MELT ADHESIVES, PLASTICIZER AND SOLVENT | JOHNSON MATTHEY & CO., LIMITED (EN) | 1977-04-19 | — | — | US | claimed |
| US-3950294-A | AQUEOUS COATING COMPOSITIONS OF DISPERSIONS OF THERMOPLASTIC ADDITION POLYMERS WITH LOW MOLECULAR WEIGHT PLASTICIZERS | CONNELLY WILLIAM | 1976-04-13 | — | — | US | claimed |