Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380827 | 0.87 | L3MBTL1 (0.48) | DPP4L3MBTL1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL5719246 | 0.87 | L3MBTL1 (0.45) | HTR2ADPP4L3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL5772349 | 0.86 | HTR2A (0.48) | HTR2ADPP4L3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL5719678 | 0.84 | DPP4 (0.68) | HTR2ADPP4L3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL6383562 | 0.84 | L3MBTL1 (0.56) | DPP4L3MBTL1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL6381744 | 0.84 | GRM5 (0.40) | L3MBTL1ALDH1A1SMN1; SMN2MAOBMAPK1 | |
| SCHEMBL4177681 | 0.83 | L3MBTL1 (0.40) | DPP4L3MBTL1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL5719021 | 0.78 | L3MBTL1 (0.42) | DPP4L3MBTL1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL6409570 | 0.78 | MAOB (0.38) | DPP4L3MBTL1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL5792563 | 0.77 | DPP4 (0.56) | DPP4L3MBTL1ALDH1A1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060094722-A1 | Combination drug | EISAI CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094722-A1 | Combination drug | DPP4, GLP1R, DPP7 | HTR2A 1018/4885DPP4 1/4885L3MBTL1 4196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.