Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5719186 | 0.88 | L3MBTL1 (0.44) | L3MBTL1HIF1AALDH1A1POLBDPP4 | |
| SCHEMBL5771254 | 0.87 | HTR2A (0.50) | L3MBTL1HIF1AALDH1A1DPP4NPSR1 | |
| Trifluoroacetic Acid SCHEMBL5719504 | 0.85 | DPP4 (0.50) | L3MBTL1HIF1AALDH1A1POLBDPP4 | |
| SCHEMBL4177681 | 0.84 | L3MBTL1 (0.40) | L3MBTL1HIF1AALDH1A1DPP4NPSR1 | |
| SCHEMBL5719021 | 0.82 | L3MBTL1 (0.42) | L3MBTL1HIF1AALDH1A1DPP4NPSR1 | |
| SCHEMBL5792563 | 0.82 | DPP4 (0.56) | L3MBTL1HIF1AALDH1A1DPP4NPSR1 | |
| SCHEMBL5718793 | 0.80 | MEN1 (0.42) | L3MBTL1HIF1AALDH1A1POLBDPP4 | |
| Trifluoroacetic Acid SCHEMBL5719312 | 0.78 | DPP4 (0.50) | L3MBTL1ALDH1A1POLBDPP4NPSR1 | |
| SCHEMBL5789419 | 0.78 | DPP4 (0.46) | L3MBTL1HIF1AALDH1A1DPP4NPSR1 | |
| Trifluoroacetic Acid SCHEMBL5718920 | 0.78 | DPP4 (0.51) | L3MBTL1HIF1AALDH1A1DPP4NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1557165-A1 | COMBINATION DRUG | Eisai Co., Ltd. (JP) | 2005-07-27 | — | — | EP | disclosed |