Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 4/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 4/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 2/20 | 0.47 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | PLAT | P00750 | 2/20 | 0.47 |
| ▸ | KLK8 | O60259 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | KLK4 | Q9Y5K2 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL591895 | 0.81 | CTSK (0.59) | ATMCTSKELANECTRB1CTSS | |
| SCHEMBL2627373 | 0.81 | CTSK (0.59) | ATMCTSKELANECTRB1CTSS | |
| SCHEMBL591894 | 0.81 | CTSK (0.59) | ATMCTSKELANECTRB1CTSS | |
| SCHEMBL7372298 | 0.81 | ATM (0.61) | ATMCTSKELANECTRB1CTSS | |
| SCHEMBL9619638 | 0.79 | ATM (0.56) | ATMCTSKELANECTRB1CTSS | |
| Acetic Acid SCHEMBL31502286 | 0.79 | CTSK (0.56) | ATMCTSKELANECTRB1CTSS | |
| SCHEMBL7305552 | 0.79 | ECE1 (0.64) | ATMCTSKELANECTSSCTSL | |
| SCHEMBL13973861 | 0.79 | ECE1 (0.64) | ATMCTSKELANECTSSCTSL | |
| SCHEMBL7331078 | 0.79 | ECE1 (0.64) | ATMCTSKELANECTSSCTSL | |
| SCHEMBL16492790 | 0.78 | ATM (0.52) | ATMCTSKELANECTRB1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613319-A2 | SUBSTITUTED PHENYL ACETAMIDES AND THEIR USE AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004091613-A2 | SUBSTITUTED PHENYL ACETAMIDES AND THEIR USE AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2004-10-28 | — | — | WO | disclosed |