Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | CTSK | P43235 | 7/20 | 0.58 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.57 |
| ▸ | ELANE | P08246 | 2/20 | 0.57 |
| ▸ | CTSS | P25774 | 7/20 | 0.56 |
| ▸ | CTSL | P07711 | 6/20 | 0.56 |
| ▸ | CTSB | P07858 | 4/20 | 0.54 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308291 | 0.86 | ATM (0.64) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL8041576 | 0.86 | ATM (0.64) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL9114401 | 0.86 | ALDH1A1 (0.57) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL8495588 | 0.85 | MAPK1 (0.55) | ATMCTSKCTSSCTSLCTSB | |
| SCHEMBL11094221 | 0.85 | ATM (0.62) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL22808751 | 0.85 | ATM (0.62) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL2059541 | 0.85 | ATM (0.62) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL23501482 | 0.84 | ATM (0.56) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL9619638 | 0.84 | ATM (0.56) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL13017006 | 0.84 | ATM (0.56) | ATMCTSKCTRB1ELANECTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268338-B1 | USEFUL AS AN ANTIBIOTIC, ESPECIALLY AS AN ANTIFUNGAL AGENT OR AS AN ANTIPROTOZOAL AGENT. | MERCK & CO., INC. | 2001-07-31 | — | — | US | disclosed |
| US-5914313-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1999-06-22 | — | — | US | disclosed |
| EP-0707488-A4 | CYCLOHEXAPEPTIDYL AMINE COMPOUNDS | MERCK & CO INC (US) | 1998-01-14 | — | — | EP | disclosed |
| EP-0707488-A1 | CYCLOHEXAPEPTIDYL AMINE COMPOUNDS | MERCK & CO. INC. (US) | 1996-04-24 | — | — | EP | disclosed |
| WO-1994025048-A1 | CYCLOHEXAPEPTIDYL AMINE COMPOUNDS | MERCK & CO., INC. (US) | 1994-11-10 | — | — | WO | disclosed |
| WO-1994009033-A1 | AN IMPROVED PROCESS FOR CYCLOHEXAPEPTIDYL BISAMINE COMPOUNDS | MERCK & CO., INC. (US) | 1994-04-28 | — | — | WO | disclosed |