Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 9/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799819 | 1.00 | SLC2A1 (0.49) | SLC2A1KCNH2L3MBTL1HTR1ALMNA | |
| SCHEMBL5774577 | 0.86 | SLC2A1 (0.49) | SLC2A1KCNH2L3MBTL1LMNAGAA | |
| SCHEMBL5773715 | 0.85 | SLC2A1 (0.39) | SLC2A1KCNH2L3MBTL1HTR1A | |
| SCHEMBL4277393 | 0.85 | SLC2A1 (0.64) | SLC2A1KCNH2 | |
| SCHEMBL4423467 | 0.85 | SLC2A1 (0.64) | SLC2A1KCNH2 | |
| SCHEMBL5754730 | 0.78 | SLC2A1 (0.56) | SLC2A1KCNH2 | |
| SCHEMBL4275555 | 0.77 | SLC2A1 (0.67) | SLC2A1KCNH2 | |
| SCHEMBL6484670 | 0.76 | NCF1 (0.58) | SLC2A1KCNH2 | |
| SCHEMBL5757621 | 0.76 | NCF1 (0.58) | SLC2A1KCNH2 | |
| SCHEMBL6484668 | 0.76 | NCF1 (0.58) | SLC2A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343780-B1 | PIPERAZINE DERIVATIVES FOR TREATMENT OF BACTERIAL INFECTIONS | SMITHKLINE BEECHAM PLC (GB) | 2006-09-20 | — | — | EP | claimed |
| EP-1343780-B1 | PIPERAZINE DERIVATIVES FOR TREATMENT OF BACTERIAL INFECTIONS | SMITHKLINE BEECHAM PLC (GB) | 2006-09-20 | — | — | EP | disclosed |
| EP-1343780-A1 | PIPERAZINE DERIVATIVES FOR TREATMENT OF BACTERIAL INFECTIONS | SMITHKLINE BEECHAM PLC (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002050061-A1 | PIPERAZINE DERIVATIVES FOR TREATMENT OF BACTERIAL INFECTIONS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-27 | — | — | WO | disclosed |