Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 4/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.39 |
| ▸ | CDK9 | P50750 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5776914 | 0.88 | MEN1 (0.40) | SLC2A1PARP1DRD2DRD1MEN1 | |
| SCHEMBL5799819 | 0.85 | SLC2A1 (0.49) | SLC2A1KCNH2HTR1AL3MBTL1 | |
| SCHEMBL5771529 | 0.85 | SLC2A1 (0.49) | SLC2A1KCNH2HTR1AL3MBTL1 | |
| SCHEMBL5778323 | 0.79 | SLC2A1 (0.49) | SLC2A1CCNT1CDK9KCNH2 | |
| SCHEMBL5774577 | 0.76 | SLC2A1 (0.49) | SLC2A1KCNH2L3MBTL1 | |
| SCHEMBL5772802 | 0.76 | SLC2A1 (0.48) | SLC2A1CCNT1CDK9DRD2MEN1 | |
| SCHEMBL6626086 | 0.75 | HTR1A (0.47) | SLC2A1DRD2DRD1MEN1KMT2A | |
| SCHEMBL5760090 | 0.75 | ABCB1 (0.47) | DRD2ADRA1BTMEM97HTR1AKDM4E | |
| SCHEMBL5774194 | 0.75 | SLC2A1 (0.49) | SLC2A1CCNT1CDK9KCNH2HTR1A | |
| SCHEMBL5754830 | 0.74 | RECQL (0.41) | SLC2A1CCNT1CDK9DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343780-B1 | PIPERAZINE DERIVATIVES FOR TREATMENT OF BACTERIAL INFECTIONS | SMITHKLINE BEECHAM PLC (GB) | 2006-09-20 | — | — | EP | claimed |