SCHEMBL5771579

SCHEMBL5771579

CC(C)OC(=O)c1cc(-c2ccc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.34
HPGD P15428 2/20 0.34
LMNA P02545 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 3/20 0.34
ALDH1A1 P00352 3/20 0.34
GAA P10253 3/20 0.34
NPC1 O15118 3/20 0.34
THRB P10828 1/20 0.33
POLB P06746 1/20 0.33
METAP2 P50579 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA7 P43166 2/20 0.32
CA9 Q16790 2/20 0.32
CA14 Q9ULX7 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5775231 0.87 RAB9A (0.37) HPGDLMNASMN1; SMN2RAB9AALDH1A1
SCHEMBL5774874 0.84 RAB9A (0.37) PDK2HPGDLMNASMN1; SMN2RAB9A
SCHEMBL5775181 0.80 HPGD (0.35) HPGDLMNASMN1; SMN2MAPTRAB9A
SCHEMBL5775093 0.77 HSD11B1 (0.36) HPGDLMNASMN1; SMN2RAB9AALDH1A1
SCHEMBL5776527 0.77 HSD11B1 (0.39) HPGDLMNASMN1; SMN2RAB9AALDH1A1
SCHEMBL5773816 0.76 BRD4 (0.39) HPGDLMNASMN1; SMN2RAB9AALDH1A1
SCHEMBL5773573 0.75 IDH1 (0.36) HPGDLMNASMN1; SMN2RAB9AALDH1A1
SCHEMBL5775225 0.75 RAB9A (0.35) HPGDLMNASMN1; SMN2RAB9AALDH1A1
SCHEMBL5776373 0.74 HSD11B1 (0.34) LMNASMN1; SMN2RAB9AALDH1A1GAA
SCHEMBL5771984 0.74 HSD11B1 (0.34) LMNASMN1; SMN2RAB9AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885885-B1 PYRIDONE DERIVATIVES AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO (JP) 2006-01-04 EP disclosed
US-6472348-B1 Pyridone derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2002-10-29 US disclosed
US-6265349-B1 Pyridone derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD (JP) 2001-07-24 US disclosed
US-6048823-A Pyridone derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2000-04-11 US disclosed
EP-0885885-A1 PYRIDONE DERIVATIVES AND HERBICIDES KumaiI Chemical Industry Co., Ltd. (JP) 1998-12-23 EP disclosed