Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.69 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.57 |
| ▸ | PRKCI | P41743 | 4/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5774401 | 0.99 | NPY5R (0.67) | NPY5RTLR7PRKCIKCNH2NPC1 | |
| SCHEMBL5773316 | 0.81 | NPY5R (1.00) | NPY5RPRKCINPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL5774363 | 0.81 | NPY5R (0.97) | NPY5RPRKCINPC1RAB9AKDM4E | |
| SCHEMBL5773650 | 0.76 | NPC1 (0.42) | NPY5RTLR7PRKCIKCNH2NPC1 | |
| SCHEMBL5770930 | 0.74 | NPY5R (1.00) | NPY5R | |
| Hydrochloric Acid SCHEMBL5772560 | 0.72 | NPY5R (0.95) | NPY5R | |
| Hydrochloric Acid SCHEMBL5773169 | 0.71 | NPY5R (0.74) | NPY5RPRKCIKCNH2SMN1; SMN2 | |
| SCHEMBL5771155 | 0.70 | NPY5R (0.78) | NPY5RPRKCIKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14034104 | 0.70 | NPY5R (0.57) | NPY5RPRKCIKDM4EMAPK1ALDH1A1 | |
| SCHEMBL14986505 | 0.70 | PRKCI (1.00) | NPY5RPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054887-B1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2006-04-12 | — | — | EP | claimed |