Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.40 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773359 | 0.82 | HTT (0.53) | GAAALDH1A1HTTKMT2AMAPT | |
| SCHEMBL5773042 | 0.81 | IDO1 (0.48) | ALDH1A1HTTKMT2AMEN1BRD4 | |
| SCHEMBL7308514 | 0.81 | GAA (0.51) | GAAALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1466280 | 0.80 | ALDH1A1 (0.50) | GAAALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29896410 | 0.80 | ALDH1A1 (0.50) | GAAALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7308745 | 0.78 | AR (0.41) | KDM4EGAAALDH1A1HTTKMT2A | |
| SCHEMBL27535793 | 0.77 | ASH1L (0.43) | GAAALDH1A1CYP2D6KMT2APRKAA1 | |
| SCHEMBL5775365 | 0.77 | SLC6A2 (0.41) | KDM4EALDH1A1CYP1A2CYP2D6HTT | |
| SCHEMBL7308476 | 0.77 | ALDH1A1 (0.43) | ALDH1A1CYP2D6HTT | |
| SCHEMBL10746888 | 0.76 | BRD4 (0.43) | KDM4EALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409485-B1 | IMMUNOMODULATING COMPOUNDS | ACTIVE BIOTECH AB (SE) | 2006-04-26 | — | — | EP | claimed |
| CN-1249063-C | Novel Immunomodulatory Compounds | ACTIVE BIOTECH AB (SE) | 2006-04-05 | — | — | CN | claimed |
| CN-1522254-A | Novel Immunomodulatory Compounds | ��Ծ���＼���ɷݹ�˾ | 2004-08-18 | — | — | CN | claimed |
| US-6642249-B2 | 3-Oxo-pyrazolo(4,3-c) -quinolin-2-yl, -thiochroman-2-yl, or -chromen-2-yl derivatives; CD80 antagonists | ACTIVE BIOTECH AB (SE) | 2003-11-04 | — | — | US | claimed |
| US-20030022913-A1 | Novel immunomodulating compounds | ACTIVE BIOTECH AB (SE) | 2003-01-30 | — | — | US | claimed |
| WO-2015090631-A1 | THERAPEUTIC TARGETS AND AGENTS USEFUL IN TREATING ISCHEMIA REPERFUSION INJURY | CARDIO3 BIOSCIENCES S.A. (BE) | 2015-06-25 | — | — | WO | disclosed |
| EP-2883883-A1 | Therapeutic targets and agents useful in treating ischemia reperfusion injury | Cardio3 Biosciences S.A. (BE) | 2015-06-17 | — | — | EP | disclosed |
| EP-1409485-B1 | IMMUNOMODULATING COMPOUNDS | ACTIVE BIOTECH AB (SE) | 2006-04-26 | — | — | EP | disclosed |
| CN-1249063-C | Novel Immunomodulatory Compounds | ACTIVE BIOTECH AB (SE) | 2006-04-05 | — | — | CN | disclosed |
| CN-1522254-A | Novel Immunomodulatory Compounds | ��Ծ���＼���ɷݹ�˾ | 2004-08-18 | — | — | CN | disclosed |
| US-6642249-B2 | 3-Oxo-pyrazolo(4,3-c) -quinolin-2-yl, -thiochroman-2-yl, or -chromen-2-yl derivatives; CD80 antagonists | ACTIVE BIOTECH AB (SE) | 2003-11-04 | — | — | US | disclosed |
| US-20030022913-A1 | Novel immunomodulating compounds | ACTIVE BIOTECH AB (SE) | 2003-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030022913-A1 | Novel immunomodulating compounds | CD40, ICOS, CD40LG | KDM4E 2144/4885GAA 2651/4885ALDH1A1 4058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.