Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24233562 | 0.93 | HTR2B (0.49) | CYP2D6CYP2C9HTR2BL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30483207 | 0.83 | CYP2D6 (0.53) | CYP2D6CYP2C9HTR2BNPC1RAB9A | |
| SCHEMBL17559359 | 0.82 | HTR2B (0.55) | HTR2BL3MBTL1ALDH1A1 | |
| SCHEMBL1298836 | 0.78 | HTR2B (0.80) | HTR2B | |
| SCHEMBL5329940 | 0.77 | NPC1 (0.49) | NPC1RAB9AKDM4EKMOHSD17B10 | |
| SCHEMBL17115816 | 0.77 | HPGDS (0.51) | HTR2BKDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL31289478 | 0.77 | KDM4E (0.76) | CYP2D6CYP2C9HTR2BNPC1RAB9A | |
| SCHEMBL13413905 | 0.77 | NPC1 (0.78) | CYP2D6CYP2C9NPC1RAB9AKDM4E | |
| SCHEMBL27741588 | 0.77 | NPC1 (0.56) | CYP2D6CYP2C9HTR2BNPC1RAB9A | |
| SCHEMBL14447532 | 0.75 | RAB9A (0.55) | CYP2D6CYP2C9NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651631-A1 | BICYCLIC IMIDAZOL DERIVATIVES AGAINST FLAVIVIRIDAE | GENELABS TECHNOLOGIES, INC. (US) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005012288-A1 | BICYCLIC IMIDAZOL DERIVATIVES AGAINST FLAVIVIRIDAE | GENELABS TECHNOLOGIES, INC (US) | 2005-02-10 | — | — | WO | disclosed |