Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777479 | 0.83 | KMT2A (0.40) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL5771888 | 0.82 | MAPK10 (0.44) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL5778071 | 0.82 | TSHR (0.41) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL5771541 | 0.82 | KMT2A (0.44) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL5774898 | 0.81 | KMT2A (0.46) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL5751401 | 0.79 | KDM4E (0.39) | TSHRTDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL5770706 | 0.78 | KMT2A (0.46) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL5749052 | 0.77 | KMT2A (0.55) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL5776931 | 0.77 | APAF1 (0.46) | TSHRTDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL5748045 | 0.76 | KMT2A (0.49) | TSHRTDP1L3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |