Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773855 | 0.87 | APAF1 (0.47) | APAF1TDP2CDC25BCASP6RCE1 | |
| SCHEMBL5775081 | 0.83 | APAF1 (0.56) | APAF1TDP2CDC25BCASP6RCE1 | |
| SCHEMBL5769647 | 0.83 | IGF1R (0.44) | APAF1TDP2CDC25BCASP6RCE1 | |
| SCHEMBL5778237 | 0.79 | APAF1 (0.47) | APAF1TDP2CDC25BCASP6RCE1 | |
| SCHEMBL5773734 | 0.79 | APAF1 (0.50) | APAF1TDP2CDC25BCASP6RCE1 | |
| SCHEMBL5775866 | 0.77 | APAF1 (0.45) | APAF1TDP2CDC25BCASP6RCE1 | |
| SCHEMBL5772841 | 0.77 | TSHR (0.42) | APAF1TDP2CDC25BCASP6RCE1 | |
| SCHEMBL28718838 | 0.76 | CYP1A2 (0.49) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL5777479 | 0.73 | KMT2A (0.40) | APAF1TDP2CDC25BCASP6RCE1 | |
| SCHEMBL5771541 | 0.72 | KMT2A (0.44) | APAF1TDP2CDC25BCASP6RCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |