Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 12/20 | 0.39 |
| ▸ | RPLP1 | P05386 | 2/20 | 0.37 |
| ▸ | RPLP0 | P05388 | 2/20 | 0.37 |
| ▸ | RPS17 | P08708 | 2/20 | 0.37 |
| ▸ | RPSA | P08865 | 2/20 | 0.37 |
| ▸ | RPS2 | P15880 | 2/20 | 0.37 |
| ▸ | RPL35A | P18077 | 2/20 | 0.37 |
| ▸ | RPL7 | P18124 | 2/20 | 0.37 |
| ▸ | RPL17 | P18621 | 2/20 | 0.37 |
| ▸ | RPS4Y1 | P22090 | 2/20 | 0.37 |
| ▸ | RPS3 | P23396 | 2/20 | 0.37 |
| ▸ | RPS12 | P25398 | 2/20 | 0.37 |
| ▸ | RPL13 | P26373 | 2/20 | 0.37 |
| ▸ | RPL10 | P27635 | 2/20 | 0.37 |
| ▸ | RPL12 | P30050 | 2/20 | 0.37 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 2/20 | 0.37 |
| ▸ | RPL22 | P35268 | 2/20 | 0.37 |
| ▸ | RPL4 | P36578 | 2/20 | 0.37 |
| ▸ | RPS19 | P39019 | 2/20 | 0.37 |
| ▸ | RPL3 | P39023 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4443673 | 0.81 | RPLP1 (0.34) | RPLP1RPLP0RPS17RPSARPS2 | |
| SCHEMBL4434418 | 0.79 | RPLP1 (0.34) | RPLP1RPLP0RPS17RPSARPS2 | |
| SCHEMBL4437552 | 0.78 | SLC6A2 (0.39) | KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4434892 | 0.78 | MCOLN3 (0.35) | RPLP1RPLP0RPS17RPSARPS2 | |
| SCHEMBL4433912 | 0.77 | FLT3 (0.35) | RPLP1RPLP0RPS17RPSARPS2 | |
| SCHEMBL4445222 | 0.77 | RPLP1 (0.40) | RPLP1RPLP0RPS17RPSARPS2 | |
| SCHEMBL5262268 | 0.76 | MAPT (0.40) | KCNH2SLC6A4 | |
| SCHEMBL4445337 | 0.76 | MAPT (0.40) | KCNH2SLC6A4 | |
| SCHEMBL9905303 | 0.76 | SLC6A2 (0.48) | RPLP1RPLP0RPS17RPSARPS2 | |
| SCHEMBL9085375 | 0.76 | SLC6A2 (0.48) | RPLP1RPLP0RPS17RPSARPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638935-A1 | NK1 ANTAGONIST | Pfizer Products Inc. (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004110996-A1 | NK1 ANTAGONIST | PFIZER PRODUCTS INC. (US) | 2004-12-23 | — | — | WO | disclosed |