Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5772883 | 1.00 | OPRM1 (0.44) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL5772887 | 1.00 | OPRM1 (0.44) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL4879205 | 0.90 | DPP4 (0.50) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL4879198 | 0.90 | DPP4 (0.50) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL4879203 | 0.90 | DPP4 (0.50) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL4878471 | 0.90 | OPRM1 (0.46) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL4878461 | 0.90 | OPRM1 (0.46) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL4870930 | 0.87 | MGLL (0.42) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL4870923 | 0.87 | MGLL (0.42) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL4870919 | 0.87 | MGLL (0.42) | OPRM1OPRD1OPRK1OPRL1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1736467-A1 | NOVEL SULFONAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-12-27 | — | — | EP | disclosed |