Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881659 | 0.86 | P2RX7 (0.67) | P2RX7 | |
| SCHEMBL5821316 | 0.81 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL4039802 | 0.81 | P2RX7 (0.58) | P2RX7 | |
| SCHEMBL7517360 | 0.81 | P2RX7 (0.72) | P2RX7 | |
| SCHEMBL8080894 | 0.80 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL7690936 | 0.80 | P2RX7 (0.73) | P2RX7 | |
| SCHEMBL4095273 | 0.80 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL6497265 | 0.80 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL7522787 | 0.78 | P2RX7 (0.58) | P2RX7 | |
| SCHEMBL5138454 | 0.78 | P2RX7 (0.51) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292590-B1 | ADMANTANE DERIVATIVES | ASTRAZENECA AB (SE) | 2006-01-18 | — | — | EP | disclosed |
| EP-1292590-A1 | ADMANTANE DERIVATIVES | AstraZeneca AB (SE) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001094338-A1 | ADMANTANE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-12-13 | — | — | WO | disclosed |