SCHEMBL5773728

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27604333	0.86	DPP4 (0.45)	MEN1KMT2A
	SCHEMBL2962148	0.80	ACHE (0.46)	MEN1KMT2AACHECKS1BSKP1
	SCHEMBL5719159	0.80	POLB (0.67)	MEN1KMT2AMAPT
	SCHEMBL2962803	0.78	ACHE (0.54)	MEN1KMT2AACHECKS1BSKP1
	SCHEMBL2964910	0.74	ACHE (0.43)	ACHECKS1BSKP1SKP2OPRD1
	SCHEMBL2964266	0.73	ACHE (0.43)	MEN1KMT2AACHECKS1BSKP1
	SCHEMBL13217753	0.73	KCNH2 (0.47)	MEN1KMT2AACHECKS1BSKP1
	SCHEMBL5719356	0.72	ALDH1A1 (0.55)	MEN1KMT2AMAPT
	SCHEMBL5719592	0.71	ALDH1A1 (0.76)	MAPT
	SCHEMBL13217695	0.71	KCNH2 (0.46)	MEN1KMT2AACHECKS1BSKP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.