Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777107 | 0.89 | CYP3A4 (0.37) | KDM4EMAPTLMNAHTTNPSR1 | |
| SCHEMBL8189104 | 0.80 | KDM4E (0.36) | KDM4EMAPTLMNAHTTNPSR1 | |
| SCHEMBL5770810 | 0.79 | SMN1; SMN2 (0.36) | MAPTLMNAHTTALDH1A1MEN1 | |
| SCHEMBL5771916 | 0.78 | HSD11B1 (0.39) | KDM4EMAPTLMNAHTTNPSR1 | |
| SCHEMBL5771668 | 0.76 | RAB9A (0.38) | LMNAHTTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL5771977 | 0.76 | MEN1 (0.37) | MAPTLMNAHTTTDP1ALDH1A1 | |
| SCHEMBL5775116 | 0.74 | HSD11B1 (0.47) | LMNAALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL5776527 | 0.74 | HSD11B1 (0.39) | LMNAALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL5775093 | 0.74 | HSD11B1 (0.36) | LMNAALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL5776472 | 0.73 | BRD4 (0.50) | LMNAHTTNPSR1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885885-B1 | PYRIDONE DERIVATIVES AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2006-01-04 | — | — | EP | disclosed |
| US-6472348-B1 | Pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2002-10-29 | — | — | US | disclosed |
| US-6265349-B1 | Pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD (JP) | 2001-07-24 | — | — | US | disclosed |
| US-6048823-A | Pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0885885-A1 | PYRIDONE DERIVATIVES AND HERBICIDES | KumaiI Chemical Industry Co., Ltd. (JP) | 1998-12-23 | — | — | EP | disclosed |