SCHEMBL5773951

SCHEMBL5773951

CCCC(=O)Oc1ccc(Cl)cc1F

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.49
PPARG P37231 6/20 0.48
PPARA Q07869 6/20 0.48
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 1/20 0.44
MRGPRX4 Q96LA9 1/20 0.43
USP30 Q70CQ3 1/20 0.42
ALDH1A1 P00352 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MAPT P10636 2/20 0.41
GAA P10253 2/20 0.40
POLB P06746 1/20 0.40
HIF1A Q16665 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2003095 0.84 ALOX15 (0.51) ALOX15TDP1L3MBTL1MAPTPOLB
SCHEMBL2708161 0.84 CYP1A2 (0.56) ALOX15CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL3837266 0.83 CYP1A2 (0.54) ALOX15CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL28921963 0.83 CYP1A2 (0.54) ALOX15CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL28980518 0.81 ALOX15 (0.46) ALOX15CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL27740419 0.81 ALOX15 (0.49) ALOX15ALDH1A1MAPTGAAPOLB
SCHEMBL11221532 0.81 ALDH1A1 (0.48) ALOX15CYP1A2CYP2C9CYP2C19MRGPRX4
SCHEMBL1665651 0.79 ALOX15 (0.47) ALOX15ALDH1A1POLB
Butyric Acid SCHEMBL28317751 0.79 TDP1 (0.53) ALOX15CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL9221817 0.79 ALOX15 (0.47) ALOX15ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885885-B1 PYRIDONE DERIVATIVES AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO (JP) 2006-01-04 EP disclosed
US-6472348-B1 Pyridone derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2002-10-29 US disclosed
US-6265349-B1 Pyridone derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD (JP) 2001-07-24 US disclosed
US-6048823-A Pyridone derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2000-04-11 US disclosed
EP-0885885-A1 PYRIDONE DERIVATIVES AND HERBICIDES KumaiI Chemical Industry Co., Ltd. (JP) 1998-12-23 EP disclosed