Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 10/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13857005 | 0.89 | SLC2A1 (0.55) | SLC2A1KCNH2NOS3NOS1NOS2 | |
| SCHEMBL5797424 | 0.84 | SLC2A1 (0.64) | SLC2A1KCNH2 | |
| SCHEMBL5775891 | 0.74 | SLC2A1 (0.53) | SLC2A1KCNH2 | |
| SCHEMBL13857009 | 0.73 | SLC2A1 (0.65) | SLC2A1KCNH2 | |
| SCHEMBL4270492 | 0.68 | SLC2A1 (0.50) | SLC2A1 | |
| SCHEMBL4270077 | 0.68 | NTRK1 (0.44) | NOS3NOS1NOS2 | |
| SCHEMBL14498791 | 0.68 | KCNH2 (0.76) | SLC2A1KCNH2 | |
| SCHEMBL14498817 | 0.67 | KCNH2 (0.50) | SLC2A1KCNH2 | |
| SCHEMBL5261779 | 0.67 | KCNH2 (0.59) | SLC2A1KCNH2 | |
| SCHEMBL5260210 | 0.67 | PDGFRB (0.41) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305308-B1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2006-12-20 | — | — | EP | claimed |