Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.53 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.52 |
| ▸ | VCP | P55072 | 3/20 | 0.47 |
| ▸ | KDR | P35968 | 9/20 | 0.45 |
| ▸ | FLT1 | P17948 | 7/20 | 0.45 |
| ▸ | FLT4 | P35916 | 7/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180766 | 0.77 | SIRT7 (0.65) | SIRT7DGAT1VCPKDRFLT1 | |
| SCHEMBL180836 | 0.75 | DGAT1 (0.56) | SIRT7DGAT1VCPKDRFLT1 | |
| SCHEMBL180938 | 0.73 | DGAT1 (0.54) | SIRT7DGAT1VCPKDRFLT1 | |
| SCHEMBL16546760 | 0.72 | DGAT1 (0.64) | SIRT7DGAT1VCPKDRFLT1 | |
| SCHEMBL14617025 | 0.72 | DGAT1 (0.64) | SIRT7DGAT1VCPKDRFLT1 | |
| SCHEMBL180807 | 0.72 | DGAT1 (0.64) | SIRT7DGAT1VCPKDRFLT1 | |
| SCHEMBL180696 | 0.71 | DGAT1 (0.64) | SIRT7DGAT1VCPKDRFLT1 | |
| SCHEMBL577407 | 0.71 | SIRT7 (0.55) | SIRT7DGAT1VCPKDRFLT1 | |
| SCHEMBL180361 | 0.69 | DGAT1 (0.81) | SIRT7DGAT1VCPKDRFLT1 | |
| SCHEMBL180949 | 0.69 | SIRT7 (0.56) | SIRT7DGAT1VCPKDRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418202-A1 | New compounds | Novartis AG (CH) | 2012-02-15 | — | — | EP | disclosed |