Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.55 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.54 |
| ▸ | VCP | P55072 | 3/20 | 0.50 |
| ▸ | KDR | P35968 | 6/20 | 0.46 |
| ▸ | FLT1 | P17948 | 5/20 | 0.46 |
| ▸ | FLT4 | P35916 | 5/20 | 0.46 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180766 | 0.78 | SIRT7 (0.65) | SIRT7DGAT1VCPKDRFLT1 | |
| SCHEMBL180970 | 0.74 | DGAT1 (0.65) | SIRT7DGAT1VCPKDRFLT1 | |
| SCHEMBL180813 | 0.73 | DGAT1 (0.79) | SIRT7DGAT1VCPKDRFLT1 | |
| SCHEMBL180836 | 0.72 | DGAT1 (0.56) | SIRT7DGAT1VCPKDRFLT1 | |
| SCHEMBL20260113 | 0.72 | VCP (0.61) | SIRT7VCPKDRFLT1FLT4 | |
| SCHEMBL180361 | 0.71 | DGAT1 (0.81) | SIRT7DGAT1VCPKDRFLT1 | |
| SCHEMBL180949 | 0.71 | SIRT7 (0.56) | SIRT7DGAT1VCPKDRFLT1 | |
| SCHEMBL577406 | 0.71 | SIRT7 (0.53) | SIRT7DGAT1VCPKDRFLT1 | |
| SCHEMBL180428 | 0.70 | DGAT1 (1.00) | SIRT7DGAT1VCPKDRFLT1 | |
| SCHEMBL180759 | 0.70 | DGAT1 (0.70) | SIRT7DGAT1VCPKDRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418202-A1 | New compounds | Novartis AG (CH) | 2012-02-15 | — | — | EP | disclosed |