Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 17/20 | 0.82 |
| ▸ | PTGDR | Q13258 | 6/20 | 0.67 |
| ▸ | PDE2A | O00408 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5774518 | 0.90 | TBXA2R (0.81) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5777289 | 0.90 | TBXA2R (1.00) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5800203 | 0.90 | TBXA2R (1.00) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5776492 | 0.89 | TBXA2R (0.79) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5835535 | 0.89 | TBXA2R (0.77) | TBXA2RPTGDR | |
| SCHEMBL5775019 | 0.86 | TBXA2R (0.85) | TBXA2RPTGDRPDE2A | |
| SCHEMBL6690976 | 0.85 | TBXA2R (0.90) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5776530 | 0.85 | TBXA2R (0.73) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5836363 | 0.82 | TBXA2R (1.00) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5777685 | 0.82 | TBXA2R (0.74) | TBXA2RPTGDRPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395590-B1 | DIHYDROPYRROLO¬1,2-A|INDOLE AND TETRAHYDROPYRIDO¬1,2-A|INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | MERCK FROSST CANADA INC (CA) | 2006-09-27 | — | — | EP | disclosed |