Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28682145 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL30932503 | 0.63 | KDM4E (0.54) | ALDH1A1KDM4EHSD17B10SMN1; SMN2KMT2A | |
| SCHEMBL29229044 | 0.63 | KDM4E (0.54) | ALDH1A1KDM4EHSD17B10SMN1; SMN2KMT2A | |
| SCHEMBL22655277 | 0.63 | MAPT (0.46) | ALDH1A1KDM4EHSD17B10TSHRHTR1A | |
| SCHEMBL4724897 | 0.62 | DPP4 (0.50) | LMNASMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL11848771 | 0.62 | TNKS (0.37) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL11004052 | 0.62 | ALDH1A1 (0.52) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL4889521 | 0.61 | TSHR (0.57) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL4202579 | 0.61 | CYP1A2 (0.35) | ALDH1A1KDM4EHSD17B10TSHRPARP1 | |
| SCHEMBL19337364 | 0.61 | MEN1 (0.41) | ALDH1A1ELANEPARP1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023046149-A1 | QUINOXALINE COMPOUND AND MEDICINAL USE THEREOF | 张文燕 | 2023-03-30 | — | — | WO | disclosed |
| EP-1670774-A1 | QUINOXALINE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005033088-A1 | QUINOXALINE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-04-14 | — | — | WO | disclosed |