Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3532509 | 0.73 | NR3C1 (0.46) | NR3C1NR3C2PGR | |
| SCHEMBL23886230 | 0.73 | KMT2A (0.37) | CTSSSLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL31697313 | 0.72 | AR (0.44) | CTSSSLC6A2SLC6A4ARKMT2A | |
| SCHEMBL22208564 | 0.72 | AR (0.44) | CTSSSLC6A2SLC6A4ARKMT2A | |
| SCHEMBL13310501 | 0.72 | CA2 (0.41) | SLC6A2SLC6A4SLC6A3KCNH2AR | |
| SCHEMBL3532136 | 0.72 | CYP2D6 (0.35) | CTSSNR3C1NR3C2PGR | |
| SCHEMBL3536311 | 0.71 | KRAS (0.37) | CTSSSLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL3657310 | 0.71 | NR3C2 (0.53) | NR3C1NR3C2PGR | |
| SCHEMBL1634224 | 0.71 | NR3C2 (0.44) | NR3C1NR3C2PGR | |
| SCHEMBL3532410 | 0.71 | NR3C1 (0.42) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638945-A1 | HETEROCYCLICALLY SUBSTITUTED PENTANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | Schering Aktiengesellschaft (DE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005003098-A1 | HETEROCYCLICALLY SUBSTITUTED PENTANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-13 | — | — | WO | disclosed |