Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5776234 | 0.90 | DPP4 (0.38) | DPP4L3MBTL1HTR2CADRB1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL2954275 | 0.88 | DPP4 (0.42) | DPP4L3MBTL1IRAK4HTR2CADRB1 | |
| Trifluoroacetic Acid SCHEMBL6414868 | 0.85 | DPP4 (0.39) | DPP4L3MBTL1IRAK4HTR2CADRB1 | |
| SCHEMBL13200001 | 0.83 | DPP4 (0.44) | DPP4L3MBTL1HTR2CADRB1ALDH1A1 | |
| SCHEMBL2954278 | 0.81 | DPP4 (0.40) | DPP4L3MBTL1HTR2CADRB1ALDH1A1 | |
| SCHEMBL6414873 | 0.80 | DPP4 (0.40) | DPP4L3MBTL1HTR2CADRB1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5271375 | 0.79 | DPP4 (0.49) | DPP4 | |
| Trifluoroacetic Acid SCHEMBL5718931 | 0.77 | DPP4 (0.42) | DPP4L3MBTL1IRAK4ADRB1ALDH1A1 | |
| SCHEMBL27623297 | 0.76 | DPP4 (0.49) | DPP4L3MBTL1HTR2CADRB1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5718943 | 0.75 | DPP4 (0.54) | DPP4L3MBTL1IRAK4HTR2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060094722-A1 | Combination drug | EISAI CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094722-A1 | Combination drug | DPP4, GLP1R, DPP7 | DPP4 1/4885L3MBTL1 4196/4885IRAK4 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.