Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2954275 | 0.89 | DPP4 (0.42) | DPP4L3MBTL1ADRB1IRAK4HTR2C | |
| Trifluoroacetic Acid SCHEMBL5776230 | 0.85 | DPP4 (0.39) | DPP4L3MBTL1ADRB1IRAK4HTR2C | |
| SCHEMBL13200001 | 0.84 | DPP4 (0.44) | DPP4L3MBTL1ADRB1HTR2CALDH1A1 | |
| SCHEMBL2954278 | 0.82 | DPP4 (0.40) | DPP4L3MBTL1ADRB1HTR2CALDH1A1 | |
| SCHEMBL6414873 | 0.81 | DPP4 (0.40) | DPP4L3MBTL1ADRB1HTR2CALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5718931 | 0.79 | DPP4 (0.42) | DPP4L3MBTL1ADRB1IRAK4BACE1 | |
| SCHEMBL5776234 | 0.79 | DPP4 (0.38) | DPP4L3MBTL1ADRB1HTR2CALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6384005 | 0.78 | DPP4 (0.47) | DPP4L3MBTL1ADRB1IRAK4HTR2C | |
| SCHEMBL27623297 | 0.78 | DPP4 (0.49) | DPP4L3MBTL1ADRB1HTR2CALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6381475 | 0.76 | DPP4 (0.52) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1514552-A1 | NOVEL FUSED IMIDAZOLE DERIVATIVE | Eisai Co., Ltd. (JP) | 2005-03-16 | — | — | EP | disclosed |