Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.30 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2954278 | 0.88 | DPP4 (0.40) | DPP4L3MBTL1HTR2CADRB1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL2954275 | 0.86 | DPP4 (0.42) | DPP4L3MBTL1HTR2CADRB1ALDH1A1 | |
| SCHEMBL13200001 | 0.84 | DPP4 (0.44) | DPP4L3MBTL1HTR2CADRB1ALDH1A1 | |
| SCHEMBL5776234 | 0.84 | DPP4 (0.38) | DPP4L3MBTL1HTR2CADRB1ALDH1A1 | |
| SCHEMBL5718922 | 0.82 | DPP4 (0.46) | DPP4L3MBTL1HTR2CADRB1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6414868 | 0.81 | DPP4 (0.39) | DPP4L3MBTL1HTR2CADRB1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5776230 | 0.80 | DPP4 (0.39) | DPP4L3MBTL1HTR2CADRB1ALDH1A1 | |
| SCHEMBL6381482 | 0.78 | DPP4 (0.51) | DPP4 | |
| SCHEMBL27623297 | 0.77 | DPP4 (0.49) | DPP4L3MBTL1HTR2CADRB1ALDH1A1 | |
| SCHEMBL5774800 | 0.77 | DPP4 (0.50) | DPP4L3MBTL1HTR2CALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1514552-A1 | NOVEL FUSED IMIDAZOLE DERIVATIVE | Eisai Co., Ltd. (JP) | 2005-03-16 | — | — | EP | disclosed |