Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 13/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773813 | 0.88 | NPY5R (0.58) | NPY5RKMT2AKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5775998 | 0.86 | NPY5R (0.56) | NPY5RKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5772751 | 0.85 | NPY5R (0.60) | NPY5RKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5769714 | 0.84 | NPY5R (0.53) | NPY5RKMT2AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL5773654 | 0.84 | NPY5R (0.52) | NPY5RKDM4EALDH1A1HPGDADORA3 | |
| Hydrochloric Acid SCHEMBL7184085 | 0.83 | NPY5R (0.58) | NPY5RKMT2AKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5776456 | 0.83 | NPY5R (0.51) | NPY5RKDM4EALDH1A1HPGDADORA3 | |
| SCHEMBL5775790 | 0.83 | NPY5R (0.61) | NPY5RKMT2ACDC7DBF4HSD17B10 | |
| SCHEMBL5771896 | 0.81 | NPY5R (0.52) | NPY5RKMT2AHSD17B10KDM4E | |
| SCHEMBL5772713 | 0.81 | NPY5R (0.48) | NPY5RADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054887-B1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2006-04-12 | — | — | EP | claimed |