Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10173266 | 0.85 | RAB9A (0.62) | RAB9AKMT2AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL1726397 | 0.84 | RAB9A (0.46) | RAB9AKMT2AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL14076028 | 0.84 | KDM4E (0.57) | RAB9AKMT2AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL14076026 | 0.81 | APP (0.71) | RAB9AKDM4ESMN1; SMN2MAPTAPP | |
| SCHEMBL2433203 | 0.77 | GAA (0.42) | RAB9AKMT2AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL1726419 | 0.76 | MAPT (0.47) | RAB9AKMT2AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL2542616 | 0.75 | RAB9A (0.50) | RAB9AKMT2AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL1985593 | 0.74 | APP (0.66) | RAB9AKMT2AKDM4ESMN1; SMN2APP | |
| SCHEMBL31154242 | 0.74 | ALDH1A1 (0.57) | RAB9AKMT2AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL1494735 | 0.73 | RAB9A (1.00) | RAB9AKMT2AKDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | RAB9A 3127/4885KMT2A 3533/4885KDM4E 4325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.