Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 12/20 | 0.45 |
| ▸ | PDE2A | O00408 | 3/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773541 | 0.91 | TBXA2R (0.55) | TBXA2RPDE2APTGDR | |
| SCHEMBL5778175 | 0.75 | TBXA2R (0.49) | TBXA2RPDE2APTGDR | |
| SCHEMBL5835835 | 0.69 | TBXA2R (0.60) | TBXA2RPDE2APTGDR | |
| SCHEMBL5773893 | 0.62 | TBXA2R (1.00) | TBXA2RPDE2APTGDR | |
| SCHEMBL15207756 | 0.59 | MAOA (0.47) | — | |
| SCHEMBL22567681 | 0.57 | MAOA (0.43) | — | |
| SCHEMBL7937917 | 0.57 | MAOA (0.52) | — | |
| SCHEMBL15208638 | 0.55 | MAOA (0.41) | — | |
| SCHEMBL3411276 | 0.54 | MAOA (0.64) | — | |
| SCHEMBL4123832 | 0.54 | MAOA (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395590-B1 | DIHYDROPYRROLO¬1,2-A|INDOLE AND TETRAHYDROPYRIDO¬1,2-A|INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | MERCK FROSST CANADA INC (CA) | 2006-09-27 | — | — | EP | disclosed |