Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777844 | 0.85 | PTGDR (0.35) | FFAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5775631 | 0.84 | GRIN2D (0.39) | FFAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5772697 | 0.82 | TBXA2R (0.37) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5779558 | 0.81 | FFAR1 (0.35) | FFAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5835091 | 0.80 | PTGS2 (0.31) | — | |
| SCHEMBL5776905 | 0.76 | PTGDR (0.42) | FFAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28537387 | 0.72 | PPARD (0.37) | FFAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5777134 | 0.69 | FFAR4 (0.35) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6731677 | 0.69 | GRIN2D (0.35) | FFAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5776227 | 0.69 | PDE2A (0.34) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395590-B1 | DIHYDROPYRROLO¬1,2-A|INDOLE AND TETRAHYDROPYRIDO¬1,2-A|INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | MERCK FROSST CANADA INC (CA) | 2006-09-27 | — | — | EP | disclosed |