Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.76 |
| ▸ | APP | P05067 | 5/20 | 0.76 |
| ▸ | SNCA | P37840 | 1/20 | 0.76 |
| ▸ | NPC1 | O15118 | 11/20 | 0.71 |
| ▸ | RAB9A | P51151 | 11/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.71 |
| ▸ | GAA | P10253 | 5/20 | 0.71 |
| ▸ | GLA | P06280 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.64 |
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.64 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.64 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 8/20 | 0.63 |
| ▸ | RORC | P51449 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178156 | 0.87 | APP (1.00) | MAPTAPPSNCANPC1RAB9A | |
| SCHEMBL2628262 | 0.87 | APP (1.00) | MAPTAPPSNCANPC1RAB9A | |
| SCHEMBL12422217 | 0.86 | MAPT (0.81) | MAPTAPPSNCANPC1RAB9A | |
| SCHEMBL13853341 | 0.84 | APP (0.94) | MAPTAPPSNCANPC1RAB9A | |
| SCHEMBL492713 | 0.83 | APP (1.00) | MAPTAPPSNCANPC1RAB9A | |
| SCHEMBL7531819 | 0.83 | MAPT (0.72) | MAPTAPPSNCANPC1RAB9A | |
| SCHEMBL13903781 | 0.83 | MAPT (0.72) | MAPTAPPSNCANPC1RAB9A | |
| SCHEMBL29466163 | 0.83 | MAPT (0.72) | MAPTAPPSNCANPC1RAB9A | |
| SCHEMBL13903820 | 0.83 | MAPT (0.72) | MAPTAPPSNCANPC1RAB9A | |
| SCHEMBL14428023 | 0.83 | MAPT (0.72) | MAPTAPPSNCANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
| WO-2001049686-A1 | S-TRIAZINE DERIVATIVES AND THEIR USE AS UV FILTERS | L'OREAL (FR) | 2001-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | MAPT 94/4885APP 1/4885SNCA 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.