SCHEMBL492713

SCHEMBL492713

Cc1ccc2nc(-c3ccc(N)cc3)sc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 15/20 1.00
MAPT P10636 7/20 1.00
KDM4E B2RXH2 4/20 1.00
GAA P10253 4/20 1.00
NPC1 O15118 3/20 1.00
RAB9A P51151 3/20 1.00
GLA P06280 3/20 1.00
SMN1; SMN2 Q16637 3/20 0.77
TP53 P04637 2/20 0.77
SNCA P37840 1/20 0.68
THRB P10828 1/20 0.63
ALDH1A1 P00352 2/20 0.62
HPGD P15428 2/20 0.62
MITF O75030 1/20 0.62
POLB P06746 1/20 0.62
NFKB1 P19838 1/20 0.62
RECQL P46063 1/20 0.62
GFER P55789 1/20 0.62
NFKB2 Q00653 1/20 0.62
RELA Q04206 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL7994519 0.98 APP (0.97) APPMAPTKDM4EGAANPC1
SCHEMBL2628249 0.97 APP (0.94) APPMAPTKDM4EGAANPC1
Ethylene SCHEMBL27827468 0.95 APP (0.91) APPMAPTKDM4EGAANPC1
1,2-Dichloroethane SCHEMBL2195018 0.93 APP (0.86) APPMAPTKDM4EGAANPC1
SCHEMBL1984424 0.92 APP (0.84) APPMAPTKDM4EGAANPC1
SCHEMBL1984426 0.92 APP (0.84) APPMAPTKDM4EGAANPC1
SCHEMBL12422217 0.90 MAPT (0.81) APPMAPTKDM4EGAANPC1
SCHEMBL8534189 0.87 MAPT (1.00) APPMAPTKDM4EGAANPC1
Hydrochlorthiazide SCHEMBL9107812 0.87 APP (0.76) APPMAPTKDM4EGAANPC1
SCHEMBL1995933 0.86 MAPT (1.00) APPMAPTKDM4EGAANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 782 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4577646-A1 ENZYMES AND USES THEREOF Samsara Eco Pty Limited (AU) 2025-07-02 EP claimed
US-20240377326-A1 USE OF FLUORESCENT OR VISIBLE TRACERS TO MONITOR NUTRIENT CONCENTRATIONS IN SOLUTION FEHR SOLUTIONS, LLC 2024-11-14 US claimed
EP-4423162-A1 REACTION INDUCED COLOR-CHANGE COMPOSITION Zephyros, Inc. (US) 2024-09-04 EP claimed
WO-2024040310-A1 ENZYMES AND USES THEREOF SAMSARA ECO PTY LIMITED (AU) 2024-02-29 WO claimed
CN-114776603-B System and method for monitoring service life of centrifugal circulating pump 江苏大学 2023-05-19 CN claimed
WO-2023076650-A1 REACTION INDUCED COLOR-CHANGE COMPOSITION ZEPHYROS, INC. (US) 2023-05-04 WO claimed
WO-2023043974-A1 USE OF FLUORESCENT TRACERS TO MONITOR NUTRIENT CONCENTRATIONS IN SOLUTION FEHR SOLUTIONS, LLC (US) 2023-03-23 WO claimed
CN-115704289-A Underwater oil production tree cap with gate valve and anti-fishing net protection frame 中油国家油气钻井装备工程技术研究中心有限公司 2023-02-17 CN claimed
CN-114776603-A Centrifugal circulating pump service life monitoring system and prediction method 江苏大学 2022-07-22 CN claimed
CN-112759770-B Functional NH2-MIL125(Ti) and preparation method and application thereof 江汉大学 2022-06-07 CN claimed
WO-1994003811-A1 IMMUNOLOGICAL DETECTION USING TWO DETECTABLE LABELS GEC-MARCONI LIMITED (GB) 1994-02-17 WO claimed
EP-0581245-A1 Water-insoluble azo colouring agents HOECHST AKTIENGESELLSCHAFT (DE) 1994-02-02 EP claimed
EP-0527186-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS The Board of Trustees for the University of Illinois (US) 1993-02-17 EP claimed
WO-1991016820-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1991-11-14 WO claimed
EP-0118086-B1 TWO-COMPONENT DIAZO TYPE MATERIAL HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-27 EP claimed
EP-0330374-A2 Method for the colorimetric determination of DPP-IV using cinnamaldehyde PROTOTEK, INC., (US) 1989-08-30 EP claimed
US-4540648-A LIGHT-SENSITIVE LAYER CONTAINING DIAZONIUM SALT, COUPLER, AND ACID STABILIZER HOECHST AKTIENGESELLSCHAFT (DE) 1985-09-10 US claimed
EP-0118086-A2 Two-component diazo type material HOECHST AKTIENGESELLSCHAFT (DE) 1984-09-12 EP claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
US-3933498-A Fogged, direct positive silver halide emulsions containing a bleach inhibiting compound and a Dmin maintainer compound E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-01-20 US claimed