Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5074958 | 0.78 | KMT2A (0.44) | KMT2AMEN1CNR1CNR2DRD2 | |
| SCHEMBL5778156 | 0.73 | ACHE (0.39) | KMT2AMEN1CNR1CNR2ACHE | |
| SCHEMBL5283241 | 0.73 | DPP4 (0.41) | KMT2AMEN1DRD3SLC6A9 | |
| SCHEMBL5466820 | 0.72 | ACHE (0.42) | ACHEALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6154961 | 0.72 | CNR1 (0.67) | CNR1CNR2MTNR1AMTNR1B | |
| SCHEMBL5969167 | 0.72 | MEN1 (0.43) | KMT2AMEN1CNR1CNR2DRD2 | |
| SCHEMBL1221931 | 0.72 | SLC6A9 (0.46) | KMT2AMEN1CNR1CNR2ALDH1A1 | |
| SCHEMBL5275770 | 0.71 | MEN1 (0.41) | KMT2AMEN1CNR1CNR2DRD2 | |
| SCHEMBL13596965 | 0.71 | DPP4 (0.58) | KMT2AMEN1CNR1CNR2DRD3 | |
| SCHEMBL5278935 | 0.71 | DPP4 (0.42) | KMT2AMEN1DRD3L3MBTL1SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687296-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | Warner-Lambert Company LLC (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005049605-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |
| WO-2005049602-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |