SCHEMBL577776

SCHEMBL577776

NC(OCCO)OCCO

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18770887 0.89 TSHR (0.35) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL925760 0.81
SCHEMBL1977379 0.79 GAA (0.33)
SCHEMBL243711 0.75
SCHEMBL2891020 0.75
SCHEMBL14917487 0.75
SCHEMBL692891 0.73
SCHEMBL22283562 0.73
Hydrochloric Acid SCHEMBL28822544 0.73
Water SCHEMBL16103959 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 631 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025242864-A1 DISCOLORING COMPOSITION FOR KERATIN FIBERS DYED WITH BLEACH-STABLE DIRECT DYES KAO CORPORATION (JP) 2025-11-27 WO claimed
US-12403074-B2 Process for permanent waving keratin fibers KAO GERMANY GMBH (DE) 2025-09-02 US claimed
US-12350360-B2 Cosmetic product for dyeing keratin fibers KAO CORPORATION (JP) 2025-07-08 US claimed
US-12350359-B2 Dyeing composition comprising direct dyes KAO CORPORATION (JP) 2025-07-08 US claimed
EP-4574877-A1 SYNTHESIS OF ACTIVATED VITRIMER ANHYDRIDE EPOXY RESIN Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2025-06-25 EP claimed
EP-3894016-B1 PROCESS FOR PERMANENT WAVING KERATIN FIBERS KAO GERMANY GMBH (DE) 2025-04-16 EP claimed
US-20250109237-A1 HIGH BIO RENEWABLE CONTENT INKS FOR LAMINATING PRINTING INKS SUN CHEMICAL CORPORATION (NJ) 2025-04-03 US claimed
EP-4511410-A1 HIGH BIO RENEWABLE CONTENT INKS FOR LAMINATING PRINTING INKS Sun Chemical Corporation (US) 2025-02-26 EP claimed
WO-2025036900-A1 HAIR DYEING COMPOSITION KAO CORPORATION (JP) 2025-02-20 WO claimed
WO-2024246126-A1 DYEING PRODUCT FOR KERATIN FIBERS COMPRISING AMMONIUM SALTS KAO CORPORATION (JP) 2024-12-05 WO claimed
WO-2008112453-A1 LOW TOXICITY SHALE HYDRATION INHIBITION AGENT AND METHOD OF USE M-I L.L.C. (US) 2008-09-18 WO claimed
US-20080227671-A1 LOW TOXICITY SHALE HYDRATION INHIBITION AGENT AND METHOD OF USE M-I L.L.C. 2008-09-18 US claimed
WO-2008112481-A1 SHALE HYDRATION INHIBITION AGENT AND METHOD OF USE M-I L.L.C. (US) 2008-09-18 WO claimed
US-6930155-B2 Powder coatings based on thermoset-modified polymers and polyesters DEGUSSA AG (DE) 2005-08-16 US claimed
US-6849705-B2 Bifunctional polyaddition compounds as crosslinkers for polyurethane powder coatings DEGUSSA AG (DE) 2005-02-01 US claimed
US-20030212239-A1 Bifunctional polyaddition compounds as crosslinkers for polyurethane powder coatings DEGUSSA AG (DE) 2003-11-13 US claimed
US-20030212205-A1 Powder coatings based on thermoset-modified polymers and polyesters DEGUSSA AG (DE) 2003-11-13 US claimed
US-20030104217-A1 Polyurethane powder coating compositions DEGUSSA AG (DE) 2003-06-05 US claimed
US-5908814-A REACTION PRODUCT OF TERTIARY AMINE AND ALKYL HALIDE M-I L.L.C. (US) 1999-06-01 US claimed
EP-0634468-A1 Drilling fluid additive and method for inhibiting hydration M-I DRILLING FLUIDS COMPANY (US) 1995-01-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12350359-B2 Dyeing composition comprising direct dyes KRT18, IK, H1-3 TSHR 2989/4885MAPK1 694/4885MEN1 1871/4885
US-12350360-B2 Cosmetic product for dyeing keratin fibers KRT18, H1-4, H1-0 TSHR 2012/4885MAPK1 101/4885MEN1 2720/4885
US-12403074-B2 Process for permanent waving keratin fibers KRT18, DSG1, DSP TSHR 4600/4885MAPK1 1657/4885MEN1 4471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.