Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 14/20 | 0.57 |
| ▸ | BCR | P11274 | 12/20 | 0.57 |
| ▸ | SRC | P12931 | 8/20 | 0.57 |
| ▸ | PRKCA | P17252 | 11/20 | 0.53 |
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | PRKACA | P17612 | 2/20 | 0.50 |
| ▸ | PRKACG | P22612 | 2/20 | 0.50 |
| ▸ | PRKACB | P22694 | 2/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 7/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.45 |
| ▸ | PRKCG | P05129 | 3/20 | 0.45 |
| ▸ | PRKCB | P05771 | 3/20 | 0.45 |
| ▸ | PRKCH | P24723 | 3/20 | 0.45 |
| ▸ | PRKCI | P41743 | 3/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5774550 | 0.93 | ABL1 (0.60) | ABL1BCRSRCPRKCAEGFR | |
| SCHEMBL5741305 | 0.88 | ABL1 (0.51) | ABL1BCRSRCPRKCAEGFR | |
| SCHEMBL6667467 | 0.82 | ABL1 (0.60) | ABL1BCRSRCPRKCAEGFR | |
| SCHEMBL5773567 | 0.81 | PRKCA (0.64) | ABL1BCRPRKCAEGFRPDGFRB | |
| SCHEMBL4903409 | 0.79 | IKBKB (0.61) | ABL1BCRSRCPRKCAPRKCD | |
| SCHEMBL17737761 | 0.76 | PRKD3 (0.59) | PRKCAPRKACAPRKACGPRKACBPRKCD | |
| SCHEMBL1789 | 0.74 | ABL1 (1.00) | ABL1BCRSRCPRKCAEGFR | |
| SCHEMBL4151825 | 0.74 | ABL1 (0.52) | ABL1BCRSRCPRKCAKMT2A | |
| SCHEMBL7524252 | 0.74 | CDK1 (0.69) | ABL1BCRSRCPRKCASYK | |
| Sulfuric Acid SCHEMBL7469444 | 0.72 | JAK2 (0.60) | ABL1BCRSRCPRKCAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395261-B1 | PYRIDYLPYRIMIDINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST PRION DISEASES | GPC BIOTECH AG (DE) | 2006-06-28 | — | — | EP | claimed |