Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | OGG1 | O15527 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777965 | 1.00 | CES2 (0.45) | CES2CES1RAB9ALMNAMAPT | |
| SCHEMBL5777969 | 1.00 | CES2 (0.45) | CES2CES1RAB9ALMNAMAPT | |
| SCHEMBL9848566 | 0.80 | ELANE (0.46) | CES2CES1LMNAMAPTKMT2A | |
| SCHEMBL29180078 | 0.80 | ELANE (0.46) | CES2CES1LMNAMAPTKMT2A | |
| SCHEMBL9848557 | 0.80 | ELANE (0.46) | CES2CES1LMNAMAPTKMT2A | |
| SCHEMBL4667898 | 0.79 | CES2 (0.53) | CES2CES1RAB9ALMNAMAPT | |
| SCHEMBL29000045 | 0.78 | CES2 (0.50) | CES2CES1RAB9ALMNAMAPT | |
| SCHEMBL17187852 | 0.69 | CES2 (0.62) | CES2CES1RAB9ALMNAMAPT | |
| SCHEMBL20102 | 0.69 | CES2 (0.62) | CES2CES1RAB9ALMNAMAPT | |
| SCHEMBL8743220 | 0.68 | CES2 (0.48) | CES2CES1RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397353-B1 | 2-(2,6-DISUBSTITUTED PHENYL)-4-ARYL-5-ALKYL-1,3-OXAZOLINE COMPOUNDS USEFUL AS INSECTICIDES AND ACARICIDES | DOW AGROSCIENCES LLC (US) | 2006-10-25 | — | — | EP | disclosed |
| US-6573286-B1 | Oxazoline compounds having a 2,6-disubstituted-phenyl group in the 2-position, an aryl or heteroaryl group in the 4-position and an alkyl group in the 5-position are effective in controlling aphids, insects and mites. | DOW AGROSCIENCES LLC | 2003-06-03 | — | — | US | disclosed |