SCHEMBL4667898

SCHEMBL4667898

C/C=C(/OC(C)=O)c1ccc(OC)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.53
CES1 P23141 2/20 0.53
CA1 P00915 6/20 0.52
CA2 P00918 6/20 0.52
MAPT P10636 2/20 0.50
PARP1 P09874 1/20 0.50
PARP10 Q53GL7 1/20 0.50
PARP2 Q9UGN5 1/20 0.50
PARP4 Q9UKK3 1/20 0.50
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C19 P33261 1/20 0.47
PLK1 P53350 1/20 0.47
F3 P13726 1/20 0.46
GSK3B P49841 1/20 0.46
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
MAPK1 P28482 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28402016 0.80 NR1I2 (0.46) CES2CES1CA1CA2MAPT
SCHEMBL5777960 0.79 CES2 (0.45) CES2CES1CA1CA2MAPT
SCHEMBL5777969 0.79 CES2 (0.45) CES2CES1CA1CA2MAPT
SCHEMBL5777965 0.79 CES2 (0.45) CES2CES1CA1CA2MAPT
SCHEMBL4998485 0.79 CA1 (0.67) CES2CES1CA1CA2MAPT
SCHEMBL9848566 0.79 ELANE (0.46) CES2CES1CA1CA2MAPT
SCHEMBL9848557 0.79 ELANE (0.46) CES2CES1CA1CA2MAPT
SCHEMBL2091071 0.78 CA1 (0.54) CES2CES1CA1CA2MAPT
SCHEMBL28586063 0.77 CA1 (0.64) CES2CES1CA1CA2MAPT
SCHEMBL3385266 0.76 MAPT (0.61) CES2CES1CA1CA2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1941870-B1 Perfume Composition comprising perilla aldehyde SHISEIDO CO LTD (JP) 2018-05-09 EP disclosed
EP-1941870-A2 Perfume Composition comprising perilla aldehyde Shiseido Co., Ltd. (JP) 2008-07-09 EP disclosed
US-7169746-B2 Perfume composition SHISEIDO CO., LTD. (JP) 2007-01-30 US disclosed
US-20040242452-A1 For effecting mental control through psycho-sedation or psycho-stimulation SHISEIDO COMPANY, LTD. (JP) 2004-12-02 US disclosed
EP-1424071-A1 PERFUME COMPOSITIONS SHISEIDO COMPANY LIMITED (JP) 2004-06-02 EP disclosed