Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.66 |
| ▸ | ATF1 | P18846 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ULK1 | O75385 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5778821 | 0.89 | CNR2 (0.68) | CNR2ATF1NFKB1CYP1A2CYP2C9 | |
| SCHEMBL5779936 | 0.84 | CNR2 (0.67) | CNR2CYP1A2CYP2C9 | |
| SCHEMBL5079708 | 0.82 | CNR2 (0.59) | CNR2ATF1NFKB1CYP1A2CYP2C9 | |
| SCHEMBL27694711 | 0.80 | CNR2 (0.72) | CNR2CYP1A2CYP2C9ULK1SIRT5 | |
| SCHEMBL5780552 | 0.80 | CNR2 (0.56) | CNR2ATF1NFKB1CYP1A2CYP2C9 | |
| SCHEMBL5782167 | 0.80 | CNR2 (0.56) | CNR2ATF1NFKB1CYP1A2CYP2C9 | |
| SCHEMBL5780688 | 0.79 | CNR2 (1.00) | CNR2CYP1A2CYP2C9SIRT5 | |
| SCHEMBL5077147 | 0.79 | CNR2 (0.55) | CNR2ATF1NFKB1CYP1A2CYP2C9 | |
| SCHEMBL5780970 | 0.76 | CNR2 (0.70) | CNR2ATF1NFKB1 | |
| SCHEMBL5780255 | 0.75 | CNR2 (0.68) | CNR2ATF1NFKB1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1736470-A2 | Pyrimidine derivatives as CB2 cannabinoid receptor modulators | GLAXO GROUP LIMITED (GB) | 2006-12-27 | — | — | EP | disclosed |