Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.60 |
| ▸ | FNTA | P49354 | 3/20 | 0.57 |
| ▸ | FNTB | P49356 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5776979 | 0.89 | RORC (0.63) | RORCFNTAFNTB | |
| SCHEMBL5781305 | 0.88 | RORC (0.65) | RORCFNTAFNTB | |
| SCHEMBL5778381 | 0.88 | RORC (0.64) | RORCFNTAFNTB | |
| SCHEMBL5782447 | 0.86 | RORC (0.54) | RORCFNTAFNTB | |
| SCHEMBL5782821 | 0.86 | RORC (0.54) | RORCFNTAFNTB | |
| SCHEMBL5782277 | 0.86 | RORC (0.54) | RORCFNTAFNTB | |
| SCHEMBL5778195 | 0.85 | RORC (0.61) | RORCFNTAFNTB | |
| SCHEMBL5778198 | 0.84 | RORC (0.52) | RORCFNTAFNTB | |
| SCHEMBL5868556 | 0.84 | RORC (0.59) | RORCFNTAFNTB | |
| SCHEMBL3559374 | 0.83 | RORC (0.58) | RORCFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053105-B2 | Farnesyl transferase inhibiting quinoline and quinazoline derivatives as farnesyl transferase inhibitors | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-05-30 | — | — | US | disclosed |
| EP-1322635-B1 | FARNESYL TRANSFERASE INHIBITING QUINOLINE AND QUINAZOLINE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2006-03-22 | — | — | EP | disclosed |
| US-20030203904-A1 | Farnesyl transferase inhibiting quinoline and quinazoline derivatives as farnesyl transferase inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203904-A1 | Farnesyl transferase inhibiting quinoline and quinazoline derivatives as farnesyl transferase inhibitors | FNTA, FNTB, RABGGTB | RORC 886/4885FNTA 1/4885FNTB 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.