Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | SNCA | P37840 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779943 | 1.00 | RAB9A (0.67) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL3273795 | 0.79 | TRPV1 (0.70) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL3273786 | 0.79 | TRPV1 (0.70) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL6791019 | 0.78 | ALDH1A1 (0.80) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL6791025 | 0.78 | ALDH1A1 (0.80) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL8641059 | 0.77 | SMN1; SMN2 (0.72) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL8641053 | 0.77 | SMN1; SMN2 (0.72) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL1424978 | 0.77 | TRPV1 (0.63) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL1424974 | 0.77 | TRPV1 (0.63) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL8065999 | 0.77 | TRPV1 (0.67) | RAB9ANPC1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652839-A2 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-1227084-B1 | DRUG DISCHARGE PUMP INHIBITORS | TRINE PHARMACEUTICALS INC (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1227084-A1 | DRUG DISCHARGE PUMP INHIBITORS | Microcide Pharmaceuticals, Inc. (US) | 2002-07-31 | — | — | EP | disclosed |