Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5770706 | 0.81 | KMT2A (0.46) | KMT2AMEN1MAPK10GFERHTT | |
| SCHEMBL5771663 | 0.81 | LRRK2 (0.42) | LRRK2KMT2AMEN1MAPK10GFER | |
| SCHEMBL5749052 | 0.80 | KMT2A (0.55) | KMT2AMEN1MAPK10GFERHTT | |
| SCHEMBL5771888 | 0.76 | MAPK10 (0.44) | KMT2AMEN1MAPK10GFERHTT | |
| SCHEMBL5780874 | 0.73 | ACP1 (0.45) | KMT2AMEN1MAPK10GFERHTT | |
| SCHEMBL5771566 | 0.73 | LRRK2 (0.43) | LRRK2KMT2AMEN1MAPK10GFER | |
| SCHEMBL5774898 | 0.73 | KMT2A (0.46) | KMT2AMEN1MAPK10GFERHTT | |
| SCHEMBL3947897 | 0.72 | MEN1 (0.66) | LRRK2KMT2AMEN1MAPK10GFER | |
| SCHEMBL5771541 | 0.71 | KMT2A (0.44) | KMT2AMEN1MAPK10GFERHTT | |
| SCHEMBL5748045 | 0.70 | KMT2A (0.49) | KMT2AMEN1MAPK10GFERHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |