Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748045 | 0.83 | KMT2A (0.49) | APAF1TDP2CDC25BCASP6RCE1 | |
| SCHEMBL5778071 | 0.81 | TSHR (0.41) | APAF1TDP2CDC25BCASP6RCE1 | |
| SCHEMBL5778374 | 0.81 | LRRK2 (0.43) | LRRK2APAF1TDP2CDC25BCASP6 | |
| SCHEMBL5771566 | 0.79 | LRRK2 (0.43) | LRRK2APAF1TDP2CDC25BCASP6 | |
| SCHEMBL5777479 | 0.78 | KMT2A (0.40) | APAF1TDP2CDC25BCASP6RCE1 | |
| SCHEMBL5747959 | 0.75 | APAF1 (0.38) | APAF1TDP2CDC25BCASP6RCE1 | |
| SCHEMBL5746906 | 0.72 | CYP1A2 (0.43) | KDM4ELMNATSHRTDP1L3MBTL1 | |
| SCHEMBL5774898 | 0.71 | KMT2A (0.46) | APAF1TDP2CDC25BCASP6RCE1 | |
| SCHEMBL5749052 | 0.69 | KMT2A (0.55) | APAF1TDP2CDC25BCASP6RCE1 | |
| SCHEMBL5772841 | 0.69 | TSHR (0.42) | APAF1TDP2CDC25BCASP6RCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |