Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779900 | 0.79 | MEN1 (0.42) | KDRAPAF1TDP2CDC25BCASP6 | |
| SCHEMBL5771663 | 0.79 | LRRK2 (0.42) | LRRK2KDRAPAF1TDP2CDC25B | |
| SCHEMBL5773720 | 0.75 | KMT2A (0.50) | APAF1TDP2CDC25BCASP6RCE1 | |
| SCHEMBL5778374 | 0.73 | LRRK2 (0.43) | LRRK2KDRAPAF1TDP2CDC25B | |
| SCHEMBL904488 | 0.73 | ALDH1A1 (0.55) | KDRAPAF1TDP2CDC25BCASP6 | |
| SCHEMBL3035542 | 0.70 | KDR (0.43) | LRRK2KDRGRM4MEN1KMT2A | |
| SCHEMBL5748045 | 0.70 | KMT2A (0.49) | KDRAPAF1TDP2CDC25BCASP6 | |
| SCHEMBL5776205 | 0.69 | KMT2A (0.61) | APAF1TDP2CDC25BCASP6RCE1 | |
| SCHEMBL16227778 | 0.68 | ABCG2 (0.57) | KDRMEN1KMT2AMAPK10GFER | |
| SCHEMBL3947897 | 0.68 | MEN1 (0.66) | LRRK2KDRMEN1KMT2AMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |