Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | JUN | P05412 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.67 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11373101 | 0.83 | RAB9A (0.67) | RAB9AMAPTKDM4ENPC1JUN | |
| SCHEMBL8230117 | 0.83 | RAB9A (0.67) | RAB9AMAPTKDM4ENPC1JUN | |
| SCHEMBL5598850 | 0.80 | MAPT (1.00) | RAB9AMAPTKDM4ENPC1JUN | |
| SCHEMBL5598852 | 0.80 | MAPT (1.00) | RAB9AMAPTKDM4ENPC1JUN | |
| SCHEMBL334615 | 0.79 | RAB9A (0.76) | RAB9AMAPTKDM4ENPC1JUN | |
| SCHEMBL29416684 | 0.79 | RAB9A (0.76) | RAB9AMAPTKDM4ENPC1JUN | |
| Hydrochloric Acid SCHEMBL11971079 | 0.79 | MAPT (0.96) | RAB9AMAPTKDM4ENPC1JUN | |
| SCHEMBL334614 | 0.79 | RAB9A (0.76) | RAB9AMAPTKDM4ENPC1JUN | |
| SCHEMBL755249 | 0.79 | RAB9A (0.76) | RAB9AMAPTKDM4ENPC1JUN | |
| Hydrochloric Acid SCHEMBL11971085 | 0.79 | MAPT (0.96) | RAB9AMAPTKDM4ENPC1JUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675585-A2 | LARGE CONDUCTANCE CALCIUM-ACTIVATED K CHANNEL OPENER | TANABE SEIYAKU CO., LTD. (JP) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005037271-A2 | LARGE CONDUCTANCE CALCIUM-ACTIVATED K CHANNEL OPENER | TANABE SEIYAKU CO., LTD. (JP) | 2005-04-28 | — | — | WO | disclosed |