Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IFNAR1 | P17181 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31167972 | 0.87 | IFNAR1 (0.60) | IFNAR1ALDH1A1LMNAMAPK1NPY1R | |
| SCHEMBL577858 | 0.87 | IFNAR1 (0.60) | IFNAR1ALDH1A1LMNAMAPK1NPY1R | |
| SCHEMBL30548749 | 0.84 | IFNAR1 (0.58) | IFNAR1ALDH1A1LMNAMAPK1NPY1R | |
| SCHEMBL1370611 | 0.77 | IFNAR1 (0.45) | IFNAR1ALDH1A1LMNAMAPK1NPY1R | |
| SCHEMBL7482207 | 0.77 | IFNAR1 (0.51) | IFNAR1ALDH1A1LMNAMAPK1NPY1R | |
| SCHEMBL20222284 | 0.75 | IFNAR1 (0.50) | IFNAR1ALDH1A1LMNAMAPK1NPY1R | |
| SCHEMBL2646 | 0.74 | ALDH1A1 (0.53) | ALDH1A1CYP1A2CYP2C9CYP2C19CYP2A6 | |
| SCHEMBL2890325 | 0.74 | IFNAR1 (0.49) | IFNAR1ALDH1A1LMNAMAPK1NPY1R | |
| SCHEMBL31490493 | 0.74 | IFNAR1 (0.49) | IFNAR1ALDH1A1LMNAMAPK1NPY1R | |
| SCHEMBL30544440 | 0.74 | HPRT1 (0.64) | IFNAR1ALDH1A1LMNAMAPK1NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239854-A1 | Body weight gain inhibitors | SUGIYAMA YASUO | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239854-A1 | Body weight gain inhibitors | PPARG, GPR119, PPARA | IFNAR1 1279/4885ALDH1A1 1312/4885LMNA 3769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.