Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5781182 | 0.90 | THRB (0.48) | THRBHSD17B10KDM4ESMN1; SMN2HPGD | |
| SCHEMBL5779112 | 0.90 | THRB (0.47) | THRBHSD17B10MAPTTSHRSMN1; SMN2 | |
| SCHEMBL5781242 | 0.88 | THRB (0.41) | THRBHSD17B10MAPTKDM4ELMNA | |
| SCHEMBL5783857 | 0.88 | THRB (0.46) | THRBHSD17B10MAPTTSHRSMN1; SMN2 | |
| SCHEMBL5783430 | 0.88 | THRB (0.46) | THRBHSD17B10MAPTTSHRSMN1; SMN2 | |
| SCHEMBL5777977 | 0.87 | THRB (0.50) | THRBHSD17B10KDM4ESMN1; SMN2HPGD | |
| SCHEMBL5782040 | 0.87 | THRB (0.45) | THRBHSD17B10SMN1; SMN2HPGDKMT2A | |
| SCHEMBL5779160 | 0.87 | THRB (0.43) | THRBHSD17B10SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL5780733 | 0.86 | THRB (0.44) | THRBHSD17B10MAPTTSHRSMN1; SMN2 | |
| SCHEMBL5781872 | 0.86 | THRB (0.41) | THRBHSD17B10KDM4ETSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194410-B1 | BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH AS (DK) | 2006-01-18 | — | — | EP | claimed |