Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5783857 | 0.93 | THRB (0.46) | THRBSMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL5779112 | 0.91 | THRB (0.47) | THRBSMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL5777903 | 0.90 | THRB (0.43) | THRBSMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL5783430 | 0.90 | THRB (0.46) | THRBSMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL5781182 | 0.89 | THRB (0.48) | THRBSMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL5780879 | 0.87 | THRB (0.43) | THRBSMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL5778632 | 0.86 | THRB (0.46) | THRBSMN1; SMN2HSD17B10KMT2AHPGD | |
| SCHEMBL5777977 | 0.86 | THRB (0.50) | THRBSMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL5782040 | 0.86 | THRB (0.45) | THRBSMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL5780592 | 0.85 | THRB (0.46) | THRBSMN1; SMN2HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194410-B1 | BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH AS (DK) | 2006-01-18 | — | — | EP | claimed |